Progesterone comes from the Mexican Wild Yam and is converted to pure USP Progesterone (meeting the standards of the United States Pharmacopeia for strength, purity and quality). Ingredients: Water (Purified), Tocopheryl Acetate (Vitamin E), Aloe Barbadensis (Aloe Vera) Leaf Juice, Carthamus Tinctorius (Hybrid Safflower) Seed Oil, Panthenol, Glycerin, Prunus Amygdalus Dulcis (Sweet Almond) Oil, Cetyl Alcohol, Glyceryl Stearate, Stearic Acid, Sodium Behenoyl Lactylate, USP Progesterone, Cholecalciferol (Vitamin D3), Phenoxyethanol, Caprylyl Glycol, Sorbic Acid, Carbomer, Potassium Hydroxide. Directions for use: Massage a dime-sized dollop of cream (1/4 teaspoon) into your skin twice daily. Try your wrists, arms, thighs, tummy, or wherever you like.